Timotor
Generic: Trimebutine Maleate
Daily Dose:
Duration:
Alternatives (2)Cheaper & Alternative Brands
Same generic (Trimebutine Maleate), same form (Tablet)
Clinical Prescribing Information
Medical monograph and safety information for healthcare professionals & patients.Indications & Clinical Uses
Timotor is indicated for-
Treatment and relief of symptoms associated with Irritable Bowel Syndrome (IBS).
Postoperative paralytic ileus in order to accelerate the resumption of the intestinal transit following abdominal surgery.
Dosage & Administration
Children over 12 years and Adults: 1 or 2 tablets, 3 times/day before meals.
Contraindications
Patients with known hypersensitivity to Trimebutine Maleate or any excipient.
Side Effects & Adverse Reactions
Timotor is generally well tolerated. The infrequently reported adverse effects are as follows: dry mouth, foul taste, diarrhea, dyspepsia, epigastric pain, nausea, constipation, drowsiness, fatigue, dizziness, hot/cold sensations, headache etc.
Warnings & Precautions
Elderly, pregnancy and lactation
Pharmacology & Mechanism of Action
Trimebutine Maleate is a noncompetitive spasmolytic agent.lt possesses moderate opiate receptor affinity and has marked anti-serotonin activity especially on 'mu' receptors. It induces regulation of spontaneous activity and increases synchronization between electrophysiological spikes and contractions in isolated guinea pig strips of colon and ileum. However, it does not alter normal motility, but regulates abnormal intestinal activity.