Trimebutine Maleate
Brand Formulations & Prices
3 brands sorted by unit price
📖 Official Clinical Monograph
DGDA Approved Prescribing GuidelinesTimotor is indicated for-
Treatment and relief of symptoms associated with Irritable Bowel Syndrome (IBS).
Postoperative paralytic ileus in order to accelerate the resumption of the intestinal transit following abdominal surgery.
Children over 12 years and Adults: 1 or 2 tablets, 3 times/day before meals.
Patients with known hypersensitivity to Trimebutine Maleate or any excipient.
Timotor is generally well tolerated. The infrequently reported adverse effects are as follows: dry mouth, foul taste, diarrhea, dyspepsia, epigastric pain, nausea, constipation, drowsiness, fatigue, dizziness, hot/cold sensations, headache etc.
Elderly, pregnancy and lactation
Trimebutine Maleate is a noncompetitive spasmolytic agent.lt possesses moderate opiate receptor affinity and has marked anti-serotonin activity especially on 'mu' receptors. It induces regulation of spontaneous activity and increases synchronization between electrophysiological spikes and contractions in isolated guinea pig strips of colon and ileum. However, it does not alter normal motility, but regulates abnormal intestinal activity.