Pvast
Generic: Ebastine
Daily Dose:
Duration:
Alternatives (12)Cheaper & Alternative Brands
Same generic (Ebastine), same form (Tablet)
Clinical Prescribing Information
Medical monograph and safety information for healthcare professionals & patients.Indications & Clinical Uses
Alestin is indicated for the symptomatic treatment of:
Seasonal and perennial allergic rhinitis.
Chronic idiopathic urticaria.
Dosage & Administration
Tablet:
Adults (more than 12 years of age)
: 10 mg (one tablet) once daily.
Children (6-12 years of age)
: 5 mg (half tablet) once daily.
Syrup:
Children (2-5 years of age)
: 2.5 ml once daily (upto 5 ml in severe cases such as Perennial Allergic Rhinitis).
Children (6-12 years of age)
: 5 ml once daily (upto 10 ml in severe cases such as Perennial Allergic Rhinitis).
Ebastine may be taken with or without food.
Contraindications
Patients with a known hypersensitivity to Ebastine or any of its ingredients.
Side Effects & Adverse Reactions
The most common side-effects are headache, dry mouth and drowsiness. Less commonly reported side effects include abdominal pain, dyspepsia, nausea and insomnia.
Pharmacology & Mechanism of Action
Ebastine is a long-acting and selective H1-histamine receptor antagonist. After repeated administration, inhibition of peripheral receptors remains at a constant level. Ebastine is rapidly absorbed and undergoes extensive first-pass metabolism following oral administration. Ebastine is almost totally converted to the pharmacologically active acid metabolite, carebastine.