OshudRivastigmine Tartrate
Drugs for Dementia
Brands & Prices (33)
📋 Indications & Uses⚠️ Contraindications⚡ Side Effects & Adverse Reactions🛡️ Warnings & Precautions🔬 Pharmacology & Mechanism
Brand Formulations & Prices
33 brands sorted by unit price
RivaCap
Rivaren
Rivatig
Vastigro
RivaCap
Benzenod
Demelon
Rebiact
Rivadem
Rivamer
Rivas
Vastigro
Benzenod
Demelon
Demelon
Rebiact
Rivadem
Rivamer
Rivaren
Rivas
Vastigro
Rivamer
Exelon
Exelon
Rivadem
Exelon
Exelon
Exelon Patch 5
Exelon Patch 15
Exelon Patch 10
Rivastigmine Amneal
Rivastigmine Amneal
Rivastigmine Amneal
📖 Official Clinical Monograph
DGDA Approved Prescribing GuidelinesBenzenod is indicated for the symptomatic treatment of mild to moderately severe Alzheimer's dementia. Symptomatic treatment of mild to moderately severe dementia in patients with Idiopathic Parkinson's disease.
The use of this medicinal product is contraindicated in patients with hypersensitivity to the active substance or other carbamate derivatives.
The most commonly reported adverse reactions are gastrointestinal, including nausea (38%) and vomiting (23%), especially during titration. Female patients in clinical studies were found to be more susceptible than male patients to gastrointestinal adverse reactions and weight loss.
Patients with sick sinus syndrome or conduction defects, resp diseases. Cholinergic stimulation may increase gastric acid secretion. May exacerbate urinary obstruction and seizures. Pregnancy. Renal impairment, mild to moderate hepatic impairment. Monitor body wt. Asthma or obstructive pulmonary disease. May worsen extrapyramidal symptoms. Lactation.
Rivastigmine is a carbamate derivative that is structurally related to physostigmine, but not to donepezil and tacrine. The precise mechanism of rivastigmine has not been fully determined, but it is suggested that rivastigmine binds reversibly with and inactivates chlolinesterase (eg. acetylcholinesterase, butyrylcholinesterase), preventing the hydrolysis of acetycholine, and thus leading to an increased concentration of acetylcholine at cholinergic synapses. The anticholinesterase activity of rivastigmine is relatively specific for brain acetylcholinesterase and butyrylcholinesterase compared with those in peripheral tissues.