Zalain
Cheaper & Alternative Brands
Same generic (Sertaconazole Nitrate [Vaginal]), same form (Vaginal Suppository)Clinical Prescribing Information
Medical monograph and safety information for healthcare professionals & patients.Indications & Clinical Uses
Sertacon VS vaginal suppository is an imidazole derivative and is a preparation that destroys fungi. The preparation is used in the local treatment of vaginal candidiasis.
Dosage & Administration
One vaginal suppository in the evening, to be inserted deeply into the vagina, preferably while lying down. If symptoms persist, repeat with a second vaginal suppository 7 days after the first administration.
Contraindications
Known hypersensitivity to any imidazole antimycotic or to any of the excipients. Concomitant use of contraceptive diaphragm.
Side Effects & Adverse Reactions
With the absence of systemic absorption of sertaconazole after the application of a vaginal suppository, side effects are unlikely to occur. However, there may be the rare occasions of allergic reactions and the manifestation of local intolerance such as a feeling of burning sensation or exacerbation of pruritus which generally disappears on discontinuation of treatment.
Warnings & Precautions
Upon confirmation of diagnosis, etiological factors causing the infection should be investigated, and patients should be counseled so as to avoid future recurrence.
Use soaps which are of neutral or alkaline pH when washing the outer genitals, as lower pH favours candidiasis.
Practice good personal hygiene; wear preferably cotton underclothes; avoid vaginal douches.
If mycosis occurs on the vulvar or perianal areas, apply an antifungal cream on these areas.
Consider the treatment of sexual partner wherever applicable for each specific case.
Do not interrupt treatment during menstruation.
Concomitant treatment for any bacterial infection associated with candidiasis is advisable.
In case of local intolerance or allergic reaction, stop treatment.
Pharmacology & Mechanism of Action
Sertaconazole is a new topical broad-spectrum antifungal. It acts against pathogenic yeasts (Candida albicans, C. tropicalis, C. spp. Pityrosporum orbiculare), dermatophytes (Trichophyton, Epidermophyton and Microsporum) and gram-positive bacteria (Staphylococcus and Streptococcus).