Visi Blue
Generic: Trypan Blue
Dose Regimen:
Course Duration:
Alternatives (1)Cheaper & Alternative Brands
Same generic (Trypan Blue), same form (Ophthalmic Solution)
Clinical Prescribing Information
Medical monograph and safety information for healthcare professionals & patients.Indications & Clinical Uses
TyBlue is indicated for use as an aid in ophthalmic surgery by staining the anterior capsule of the lens.
Dosage & Administration
The first step to administer Trypan Blue is to inject an air bubble into the anterior chamber using a 26 gauge needle. It prevents dilution of dye by the aqueous humor. Then Trypan Blue is injected into the anterior lens capsule using a tuberculin syringe. Sufficient staining is achieved as soon as the dye has contracted the capsule. If some area is left unstained, inject one more drop till it gets stained.
Contraindications
Trypan Blue is contraindicated when a non-hydrated (dry state), hydrophilic acrylic intraocular lens (IOL) is planned to be inserted into the eye because the dye may be absorbed by the IOL and stain the IOL.
Side Effects & Adverse Reactions
Discoloration of high water content hydrogen intraocular lenses.
Inadvertent staining of the posterior lens capsule and vitreous face.
It is generally self limited, lasting up to one week.
Warnings & Precautions
It is recommended that after injection all excess TyBlue should be immediately removed from the eye by thorough irrigation of the anterior chamber.
Pharmacology & Mechanism of Action
Trypan Blue is a selective tissue staining agent (dye) which stains anterior lens capsule of the human crystalline lens. The dye does not penetrate the capsule, permitting visualization of the anterior capsule in contrast to the non-stained lens cortex and inner lens material.