Solrin
Cheaper & Alternative Brands
Same generic (Aspirin), same form (Tablet (Enteric Coated))
Clinical Prescribing Information
Medical monograph and safety information for healthcare professionals & patients.Indications & Clinical Uses
Angin is indicated in the following indications-
Prophylaxis against arterial occlusive events
: Myocardial infarction, myocardial re-infarction, after bypass surgery, acute ischaemic stroke/TIA.
Mild to moderate pain
: Headache, muscle pain, dysmenorrhoea and toothache etc.
Chronic disease accompanied by pain and inflammation
: Osteoarthritis.
Antipyretic
: Cold fever and influenzae.
Dosage & Administration
Pain, inflammatory diseases and as antipyretic
: Aspirin 300 mg 1-3 tablets 6 hourly with a maximum daily dose of 4 gm.
Suspected acute coronary syndrome
: 150 mg-300 mg immediately unless there are clear contraindications.
After myocardial infarction
: Aspirin 150 mg daily for 1 month. Long-term use of aspirin in a dose of 75 mg daily is recommended thereafter.
Acute ischaemic stroke/Transient ischaemic stroke (TIA)
: The starting dose is 150 mg-300 mg daily and Aspirin 75 mg daily thereafter.
Following bypass surgery
: 75 mg-300 mg daily starting 6 hours post-procedure.
Contraindications
Aspirin is contraindicated to the children (Reye's syndrome) less than 12 years, in breast-feeding and active peptic ulcer. It is also contraindicated in bleeding due to haemophilia, intracranial haemorrhage and other ulceration.
Side Effects & Adverse Reactions
Side effects for the usual dosage of Angin are mild including nausea, dyspepsia, gastrointestinal ulceration and bronchospasm etc.
Warnings & Precautions
It should be administered cautiously in asthma, uncontrolled blood pressure, and pregnant women. It should be administered with caution to patients with a nasal polyp and nasal allergy.
Pharmacology & Mechanism of Action
By decreasing platelet aggregation, Aspirin inhibits thrombus formation on the arterial side of the circulation, where thrombi are formed by platelet aggregation and anticoagulants have little effect. Aspirin is the analgesic of choice for headache, transient musculoskeletal pain and dysmenorrhoea. It has anti-inflammatory and antipyretic properties, which may be useful. Enteric-coated Aspirin reduces intestinal disturbance and gastrointestinal ulceration due to aspirin.