Sodib
Cheaper & Alternative Brands
Same generic (Sodium Bicarbonate), same form (IV Infusion)No other brands currently registered with this exact active generic and dosage form.
Clinical Prescribing Information
Medical monograph and safety information for healthcare professionals & patients.Indications & Clinical Uses
Alkalina is indicated in-
1. Management of acidosis in cardiac arrest.
2. Alkalinization of urine.
3. Management of metabolic acidosis in:
Severe renal disease
Uncontrolled diabetes
Circulatory insufficiency from shock or dehydration
Severe primary lactic acidosis
Dosage & Administration
Oral
: The usual dose is 300 mg to 2 grams, 1 to 4 times daily.
Intravenous
(Severe metabolic acidosis):
Adult: By slow inj of a hypertonic solution of up to 8.4% (1000 mmol/L), or by continuous infusion of a weaker solution, usually 1.26% (150 mmol/L). For correction of acidosis during advanced cardiac life support procedures, 50 ml of an 8.4% solution may be given.
Elderly: Dosage adjustments may be required.
Contraindications
This drug is contraindicated in hypersensitivity hypoventilatory states, excessive chloride depletion owing to continuous gastric fluid loss from vomiting or GI suctioning, metabolic and/or respiratory alkalosis, hypocalcemia and diuretics known to produce hypochloremic alkalosis.
Side Effects & Adverse Reactions
Common side effects:
Headache
Nausea
Irritability
Notify your doctor you develop any of the following effects:
Muscle weakness
Slow reflexes
Confusion
Swelling of the feet or ankles
Black tar-like stools
Coffee-ground vomit
Warnings & Precautions
Caution should be taken for patients with pre-existing heart disease, kidney disease, liver disease, high blood pressure, any allergies because this medication contains salt (sodium), do not use it if you are on a salt restricted diet.
Pharmacology & Mechanism of Action
Sodium bicarbonate is a systemic alkalizer, which increases plasma bicarbonate, buffers excess hydrogen ion concentration, and raises blood pH, thereby reversing the clinical manifestations of acidosis. It is also a urinary alkalizer, increasing the excretion of free bicarbonate ions in the urine, thus effectively raising the urinary pH. It also replenishes electrolyte imbalance in severe diarrhea where the loss of bicarbonate can be significant.