Sinamox
Cheaper & Alternative Brands
Same generic (Amoxicillin Trihydrate), same form (Capsule)
Clinical Prescribing Information
Medical monograph and safety information for healthcare professionals & patients.Indications & Clinical Uses
Admox is indicated in the treatment of infections due to susceptible ß-lactamase negative strains of microorganisms. These infections include
Ear, nose and throat infections (i.e. otitis media, sinusitis, tonsillitis, pharyngitis, laryngitis)
Lower respiratory tract infections (i.e. pneumonia, acute and chronic bronchitis lung abscess, empyema, bronchiectasis)
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Admox is indicated in the treatment of infections due to susceptible ß-lactamase negative strains of microorganisms. These infections include
Ear, nose and throat infections (i.e. otitis media, sinusitis, tonsillitis, pharyngitis, laryngitis)
Lower respiratory tract infections (i.e. pneumonia, acute and chronic bronchitis lung abscess, empyema, bronchiectasis)
Skin and soft tissue infections (i.e. cellulitis, carbuncles, furunculosis, infected wounds, abscess)
Genito-urinary tract infections (i.e. pyelonephritis, cystitis and urethritis)
Venereal disease (i.e. acute uncomplicated gonorrhoea)
In dental abscess, it is used as short-term therapy.
It is also indicated in combination with Clarithromycin and Lansoprazole (as triple therapy), for the treatment of patients with H. pylori infection and duodenal ulcer disease and to reduce the risk of duodenal ulcer recurrence.
Contraindications
Amoxicillin is contraindicated in penicillin hypersensitive patients.
Side Effects & Adverse Reactions
Side effects are mild and transient in nature. This may include diarrhoea, indigestion or occasionally rash. Pseudo-membranous colitis has been reported rarely.
Warnings & Precautions
The possibility of superinfections with mycotic or bacterial pathogens should be kept in mind during therapy. If superinfections occur, Admox should be discontinued and appropriate therapy should be instituted.
Pharmacology & Mechanism of Action
Amoxicillin is a broad spectrum penicillin. It is effective against a wide range of Gram-positive and Gram-negative bacteria. It acts through the inhibition of biosynthesis of cell wall. Amoxicillin is stable in the presence of gastric acid and is rapidly absorbed after oral administration. After an oral dose, peak plasma concentration of Amoxicillin is reached within 1 to 2 hours. Amoxicillin is widely distributed at varying concentration in body tissues and fluids.