Salost DR
Cheaper & Alternative Brands
Same generic (Risedronate Sodium), same form (Tablet (Delayed Release))No other brands currently registered with this exact active generic and dosage form.
Clinical Prescribing Information
Medical monograph and safety information for healthcare professionals & patients.Indications & Clinical Uses
This is in a group of medicines called bisphosphonates. It alters the cycle of bone formation and breakdown in the body. It slows bone loss while increasing bone mass, which may prevent bone fractures. Risedon is a prescription medicine used:
To prevent and treat osteoporosis in postmenopausal women.
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This is in a group of medicines called bisphosphonates. It alters the cycle of bone formation and breakdown in the body. It slows bone loss while increasing bone mass, which may prevent bone fractures. Risedon is a prescription medicine used:
To prevent and treat osteoporosis in postmenopausal women.
To increase bone mass in men with osteoporosis.
To prevent and treat osteoporosis in men and women that is caused by treatment with steroid medicines such as prednisone.
To treat Paget's disease of bone in men and women.
Contraindications
Risedronate Sodium tablet is contraindicated in patients with known hypersensitivity to Risedronate Sodium and in patients with hypocalcaemia, severe renal impairment (creatinine clearance lower than 30 ml/min), during pregnancy and lactation.
Side Effects & Adverse Reactions
Serious side effects:
chest pain;
difficulty or pain when swallowing;
pain or burning under the ribs or in the back;
new or worsening heartburn;
severe joint, bone, or muscle pain; or
jaw pain, numbness, or swelling.
Less serious side effects:
mild heartburn or stomach upset;
diarrhea, gas,or constipation;
mild joint or back pain;
headache.
Warnings & Precautions
Take special care with Risedon if you:
Have low blood calcium (hypocalcemia)
Cannot sit or stand up for 30 minutes
Have kidneys that work poorly
Have an allergy to Risedon
Before taking Risedon talk to doctor if you:
Are pregnant or may become pregnant. We do not know if Risedon can harm your unborn child.
Are breast-feeding or plan to breast-feed. We do not know if Risedon can passthrough your milk and if it can harm your baby.
Have kidney problems Risedon may not be right for you.
Risedon is not intended for use in children.
During treatment, if you experience an allergic reaction (such as swelling of the face, tongue or throat, difficulty in breathing or swallowing, skin rash), you must stop taking Risedon and seek medical advice immediately. If you have stopped treatment due to hypersensitivity reactions you should not re-start therapy with Risedon.
Pharmacology & Mechanism of Action
Your body is constantly breaking down old bone and making new bone tissue. If you have osteoporosis, your body breaks down more bone than it forms so gradually bone loss occurs and your bones become thinner and fragile. This is especially common in women after menopause (change of life). Many people with osteoporosis have no symptoms and you may not even know that you have it. However, osteoporosis makes you more likely to have fractures (break bones), especially in your spine, hips and wrists.
Risedronate has an affinity for hydroxyapatite crystals in bone and acts as an antiresorptive agent. At the cellular level, Risedronat inhibits osteoclasts. The osteoclasts adhere normally to the bone surface but show evidence of reduced active resorption.