Rabix-VC
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Same generic (Rabies Vaccine), same form (IM/SC Injection)Clinical Prescribing Information
Medical monograph and safety information for healthcare professionals & patients.Indications & Clinical Uses
Rabivax is indicated for prophylactic immunization against rabies and treatment of patients following suspected rabies contact.
Pre-exposure Immunization:
Professional groups exposed to frequent contamination
Veterinary surgeons (including students at veterinary colleges)
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Rabivax is indicated for prophylactic immunization against rabies and treatment of patients following suspected rabies contact.
Pre-exposure Immunization:
Professional groups exposed to frequent contamination
Veterinary surgeons (including students at veterinary colleges)
Technical personnel working with veterinary surgeons
Laboratory personnel handling material contaminated with rabies vims
Personnel in abattoirs and knackers yards
Taxidermists
Gamekeepers, forestry workers and naturalists in enzootic areas
Infants particularly exposed to the risk of rabies
Post-exposure Immunization:
Treatment of subjects bitten by rabid animals or those suspected of being so
Treatment of contact subjects.
Contraindications
Rabies vaccine is contraindicated in the following cases:
Pre-exposure
: Severe fever, febrile infection, acute disease, progressive chronic diseases. Known hypersensitivity reactions to rabies vaccine or any of its components
Post-exposure
: No contraindication to post-exposure treatment, because rabies is lethal disease, any contraindication to exposure, treatment should be considered carefully before disqualifying an individual for anti-rabies treatment.
Side Effects & Adverse Reactions
Minor local reactions like pain, erythema, oedema, pruritus and induration at the injection site and lasting to 24-48 hours. Moderate fever, shivering, fainting, asthenia, dizziness, respiratory manifestations (dyspnoea, wheezing), fever, abdominal pain, vomiting and allergic skin reactions (urticaria, rash, itching).
Warnings & Precautions
Intravenous injection is prohibited.
The vaccine and anti-rabies immunoglobulin must not be administered with same syringe and in the same injection site.
Before use, please carefully check package, label, appearance and the validity period.
After reconstitution, the freeze-dried Rabivax should be administered as soon as possible.
Any reconstituted vaccine should be used as soon as possible. It must be stored in a refrigerator at 2°C to 8°C and used within 8 hours after reconstitution or discarded.
Pharmacology & Mechanism of Action
Rabies Vaccine for human use is a freeze-dried preparations of inactivated rabies virus produced on Vero cell. After reconstitution the vaccine is a clear, colorless sterile solution for intramuscular use.