Ornopain
Cheaper & Alternative Brands
Same generic (Lornoxicam), same form (IM/IV Injection)
Clinical Prescribing Information
Medical monograph and safety information for healthcare professionals & patients.Indications & Clinical Uses
Camlor is indicated in-
Short-term relief of acute mild to moderate pain
Symptomatic relief of pain inflammation in osteoarthritis
Symptomatic relief of pain and inflammation in rheumatoid arthritis.
Dosage & Administration
Acute Pain
: 8-16 mg Lomoxicam daily divided into 2 or 3 doses. Maximum recommended daily dose is 16 mg.
Osteoarthritis and Rheumatoid arthritis
: Initial recommended dose is 12 mg Lomoxicam daily divided into 2 or 3 doses. Maintenance dose should not exceed 16 mg Lomoxicam daily.
Use in Children & Adolescents
: Lomoxicam is not recommended for use in children and adolescents below age 18 due to lack of data on safety and efficacy.
Elderly
: No special dosage modification is required for elderly patients above age 65 but Lomoxicam should be administered with precaution as gastrointestinal adverse effects are less well tolerated in this group.
Renal Impairment
: For patients with mild to moderate renal impairment the maximum recommended daily dose is 12 mg divided in 2 or 3 doses.
Hepatic impairment
: For patients with moderate hepatic impairment, the maximum recommended daily dose is 12 mg divided in 2 or 3 doses. Undesirable effects may be minimized by using the lowest effective dose for the shortest duration necessary to control symptoms.
Contraindications
Hypersensitivity to Lomoxicam or to any of the excipients, peptic ulcer, severe hepatic impairment, severe renal impairment (Serum creatinine > 700 pmol/l) and Thrombocytopenia and the third trimester of pregnancy.
Side Effects & Adverse Reactions
The most commonly observed adverse events of NSAIDs are gastrointestinal in nature. Peptic ulcers, perforation or Gl bleeding, sometimes fatal, particularly in the elderly, may occur. Nausea, vomiting, diarrhea, flatulence, constipation, dyspepsia, abdominal pain, melaena, hematemesis, ulcerative stomatitis, exacerbation of colitis and Crohn’s disease have been reported by following administration of NSAIDs.
Warnings & Precautions
Lomoxicam should be taken carefully when someone has impaired kidney function, someone has a history of high blood pressure or heart failure, someone suffers from ulcerative colitis or Crohn’s diseases, someone has a history of bleeding tendency, someone has a history of asthma & someone suffers from SLE (Systemic Lupus Erythematosus) a rare immunological disease and women who are taking treatment for infertility.
Pharmacology & Mechanism of Action
Lomoxicam is a non- steroidal anti-inflammatory drug (NSAID) and antirheumatic drug of the oxicam class. It is intended for short term treatment of acute mild to moderate pain and symptoms of rheumatoid arthritis and osteoarthritis such as pain and inflammation of joints. Lornoxicams mode of action is mainly related to the inhibition of the prostaglandin synthesis (inhibition of the cyclooxygenase enzyme) leading to desensitization of peripheral nociceptors and consequently inhibition of inflammation.