Gyned
Cheaper & Alternative Brands
Same generic (Metronidazole + Neomycin Sulphate + Polymyxin B + Nystatin), same form (Vaginal Suppository)
Clinical Prescribing Information
Medical monograph and safety information for healthcare professionals & patients.Indications & Clinical Uses
Gynastin is indicated in-
Vaginal trichomoniasis
Vaginal leucorrhoeas
Mixed vaginal infections (Fungal or Bacterial).
Dosage & Administration
One suppository in the vagina at bedtime for 12 days or as directed by the physician.
Contraindications
Contraindicated to the patients who are hypersensitive to Metronidazole, Neomycin Sulphate, Polymyxin B Sulphate and Nystatin.
Side Effects & Adverse Reactions
Skin rash, urticaria may occur rarely.
Warnings & Precautions
Caution should be taken in case of renal impairment.
Pharmacology & Mechanism of Action
Metronidazole, a nitroimidazole, is active against various anerobic bacteria and protozoa. Nystatin is a polyene antibiotic with antifungal activity. Neomycin is an aminoglycoside. It is bactericidal and active against some gram-positive and gram-negative organisms. Polymyxin is active against gram-negative organisms including Pseudomonas aeruginosa.