Farpem
Cheaper & Alternative Brands
Same generic (Faropenem), same form (Tablet)
Clinical Prescribing Information
Medical monograph and safety information for healthcare professionals & patients.Indications & Clinical Uses
Farobac tablet is indicated in the treatment of the following infections:
Lower respiratory tract infections
: acute bronchitis, pneumonia, pulmonary suppuration.
Ear, nose, and throat (ENT) infections
: otitis externa, tympanitis, sinusitis.
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Farobac tablet is indicated in the treatment of the following infections:
Lower respiratory tract infections
: acute bronchitis, pneumonia, pulmonary suppuration.
Ear, nose, and throat (ENT) infections
: otitis externa, tympanitis, sinusitis.
Genito-urinary infections
: pyelonephritis, cystitis, prostatitis, seminal gland inflammation.
Upper respiratory tract infections
: pharyngitis, tonsillitis.
Skin and skin structure infections
: pustular acne, folliculitis, contagious impetigo, erysipelas, lymphangitis, suppurative nail inflammation, subcutaneous abscess, hidradenitis (sweat gland inflammation), infective sebaceous cyst, chronic pyoderma, secondary infection of external wounds or surgical wounds.
Gynecological infections
: adnexitis, bartholin gland inflammation.
Dosage & Administration
Upper respiratory tract infections
: 150 mg t.i.d., can be increased to 200 mg t.i.d.
ENT infections
: 200 mg t.i.d., can be increased to 300 mg t.i.d.
Lower respiratory tract infections
: 200 mg t.i.d., can be increased to 300 mg t.i.d.
Skin and skin structure infections
: 150 mg t.i.d., can be increased to 200 mg t.i.d.
Genito-urinary infections
: 200 mg t.i.d., can be increased to 300 mg t.i.d.
Gynecological infections
: 150 mg t.i.d., can be increased to 200 mg t.i.d.
Contraindications
Faropenem is contraindicated in patients with known hypersensitivity to any of the components of this product or to other drugs in the same class, or in patients who have demonstrated anaphylactic reactions to beta-lactams.
Side Effects & Adverse Reactions
Common side effects of Farobac are Headache, Nausea, Vomiting, Stomach pain and Diarrhea.
Warnings & Precautions
Farobac should be administered with caution in the following:
Patients with a past history of hypersensitivity to penicillin, cephem or carbapenem drugs.
Patients with a family history of atopy.
Patients with renal impairment. The dosage should be reduced or the interval between doses should be increased.
Geriatric patients.
Patients with poor oral intake or poor general state (since there are cases that show symptoms of vitamin K deficiency, proper monitoring should be done).
Pharmacology & Mechanism of Action
Faropenem is a penem class of antimicrobial and has bactericidal activity against a variety of gm-ve, gm+ve and anaerobic bacteria. Faropenem is bactericidal, with a strong affinity for the high molecular penicillin binding proteins (PBPs) of the cell wall, which is essential for the multiplication of bacilli; it, thus, acts by inhibiting the cell wall synthesis. Faropenem shows broad antibacterial activity against both aerobic and anaerobic Gram-positive and Gram-negative bacteria. Faropenem is highly stable against various beta lactamases and binds preferentially to the PBPs, 2 and 1A, of Escherichia coli (E. coli).