Eusoft
Cheaper & Alternative Brands
Same generic (Urea), same form (Cream)
Clinical Prescribing Information
Medical monograph and safety information for healthcare professionals & patients.Indications & Clinical Uses
Aqua Care 10% cream is indicated for-
Ichthyosis and dry skin conditions
Management of eczemas
Management of psoriasis
Dosage & Administration
Urea 10% cream is applied topically. Wash affected areas well, rinse off all traces of soap, dry and apply sparingly twice daily. Occlusive dressings may be used, but are usually unnecessary because of the self-occlusive nature of the cream.
Use in children: Urea 10% cream can be used in all age groups.
Contraindications
This is contraindicated in any other ingredient of this preaparation.
Side Effects & Adverse Reactions
No serious toxicity has been reported with topical Aqua Care. Historically it is considered a safe drug. But on some occasions, topical Aqua Care has been shown to cause burning and irritation, if applied to inflamed, broken or exudative skin eruptions.
Warnings & Precautions
In some instances, Aqua Care 10% cream may cause local irritation and edema, when applied to sensitive skin. If the condition is aggravated or there is no improvement the doctor should be consulted. Avoid application to moist or broken skin.
Pharmacology & Mechanism of Action
Topical urea is bacteriostatic, bactericidal, fungistatic, proteolytic, hygroscopic and has mild local anesthetic properties. These actions are dose dependent. Most of its therapeutic applications depend on its hygroscopic properties. The hygroscopic property is due to its ability to cause configurational change in proteins in the stratum corneum. A 10% urea cream has been shown to increase the water holding capacity of ichthyotic scale by 100% after 3 weeks of treatment. There is no information available about percutaneous absorption of urea. Therapeutic effects depend on local concentrations, not on systemic absorption of the drug. If absorbed, urea would be excreted unchanged in the urine.