Eposis
Cheaper & Alternative Brands
Same generic (Erythropoietin Alfa), same form (IV/SC Injection)
Clinical Prescribing Information
Medical monograph and safety information for healthcare professionals & patients.Indications & Clinical Uses
Epocrit is an erythropoiesis-stimulating agent (ESA) indicated for:
Treatment of anemia due to:
Chronic Kidney Disease (CKD) in patients on dialysis and not on dialysis.
Zidovudine in HIV-infected patients.
The effects of concomitant myelosuppressive chemotherapy, and upon initiation, there is a minimum of two additional months of planned chemotherapy.
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Epocrit is an erythropoiesis-stimulating agent (ESA) indicated for:
Treatment of anemia due to:
Chronic Kidney Disease (CKD) in patients on dialysis and not on dialysis.
Zidovudine in HIV-infected patients.
The effects of concomitant myelosuppressive chemotherapy, and upon initiation, there is a minimum of two additional months of planned chemotherapy.
Reduction of allogeneic RBC transfusions in patients undergoing elective, noncardiac, nonvascular surgery.
Prevention of anemia of prematurity in infants with a birth weight of 750 to 1500 gm and gestational age of less than 34 weeks.
Contraindications
Uncontrolled hypertension.
Serious allergic reactions to Erythropoietin alfa.
Patients who develop Pure Red Cell Aplasia (PRCA) following treatment with any erythropoietin should not receive Erythropoietin alfa or any other erythropoietin.
Side Effects & Adverse Reactions
Adverse reactions in 5% of Epocrit treated patients in clinical studies were:
Patients with CKD: Hypertension, arthralgia, muscle spasm, pyrexia, dizziness, medical device malfunction, vascular occlusion, and upper respiratory tract infection.
Zidovudine-treated HIV-infected Patients: Pyrexia, cough, rash, and injection site irritation.
Cancer Patients on Chemotherapy: Nausea, vomiting, myalgia, arthralgia, stomatitis, cough, weight decrease, leukopenia, bone pain, rash, hyperglycemia, headache, depression, dysphagia, hypokalemia, and thrombosis.
Surgery Patients: Nausea, vomiting, pruritus, headache, injection site pain, chills, deep vein thrombosis, cough, and hypertension.
Premature infants: A fall in serum ferritin values is very common (>10%)