Dermalog
Generic: Halcinonide
Application:
Course Duration:
Alternatives (3)Cheaper & Alternative Brands
Same generic (Halcinonide), same form (Cream)
Clinical Prescribing Information
Medical monograph and safety information for healthcare professionals & patients.Indications & Clinical Uses
Cinon cream is suitable for both wet and dry eczematous lesions. For acute and chronic corticosteroid-responsive conditions which may include psoriasis, anogenital eczema, nummular eczema and intertrigo infantile. Contact dermatitis, atopic dermatitis, dermatitis herpetiformis, neurodermatitis, seborrhoeic dermatitis.
Dosage & Administration
Adults
: Halcinonide should be applied to the affected areas 2-3 times daily. In long term therapy or where lower strength preparation are required, use intermittently.
Children
: Use minimal amount necessary for effective therapy. For effective treatment use the minimal amount, if necessary.
Contraindications
Halcinonide cream should not be applied to patients sensitive with halcinonide. It should not be used in the treatment of rosacea and discriminately for pruritus.
Side Effects & Adverse Reactions
Cinon cream is well tolerated. Where adverse reactions occur, they are usually reversible on cessation therapy. However, the following side effects have been reported usually with prolonged uses: burning, itching, irritation, dryness, folliculitis, hypertrichosis, acneform eruptions, hypopigmentation, perioral dermatitis, maceration, secondary infection, skin atrophy, striae etc.
Warnings & Precautions
Cinon cream applications should not be made with an occlusive dressing to large areas of the body because of the increased risk of systemic toxicity. In general should not be used in presence of infections particularly to the eye. It should not be applied to ulcers of the leg and long term topical use is best to be avoided, specially in children.
Pharmacology & Mechanism of Action
Halcinonide cream contains Halcinonide which is a class of primarily synthetic steroid used as topical anti-inflammatory, anti-allergic & antipruritic agent. It is highly effective in corticosteroid-responsive dermatoses because of bi-phasic base. Bi-phasic base offers immediate release of medicaments and prolonged action. On topical application, it can be absorbed from normal intact skin. Inflammation as well as other disease processes in the skin increase percutaneous absorption of halcinonide. Occlusive dressings substantially increase the percutaneous absorption of the drug. Once absorbed through the skin, topical corticosteroid is handled through pharmacokinetic pathways similar to systemically administered corticosteroids.