Compiron
Generic: Iron Polymaltose Complex
Daily Dose:
Course Duration:
Cheaper & Alternative Brands
Same generic (Iron Polymaltose Complex), same form (Pediatric Drops)No other brands currently registered with this exact active generic and dosage form.
Clinical Prescribing Information
Medical monograph and safety information for healthcare professionals & patients.Indications & Clinical Uses
Compiron syrup is indicated for the-
Treatment of latent iron deficiency and iron deficiency anaemia including macrocytic anaemia,nutritional anaemia of infants, anaemia due to excessive haemorrhage and anaemia associated with infections and malignant disease.
Prevention and treatment of iron deficiency anaemia before, during and after pregnancy and during lactation.
For prophylactic therapy of iron deficiency to cover the recommended daily dietary allowances (RDA).
Dosage & Administration
Dosage and duration of therapy are dependent upon the extent of iron deficiency and should be taken as directed by the physician.
Adults: 10 ml once or twice daily
Children (6-12 years): 10 ml daily
Children (2-6 years): 5 ml daily
Premature infants & Infants: 3.33 mg of elemental iron/kg body weight.
Contraindications
In conditions where there is a risk of iron overload e
.
g
.
haemochromatosis, thalassemia or
haemosiderosis
.
In case of hypersensitivity to iron or any other ingredients of the syrup
.
Side Effects & Adverse Reactions
Compiron is well tolerated. However, a few side effects of oral iron preparations, including nausea, vomiting, constipation or diarrhoea may occur.
Warnings & Precautions
Initially epigastric pain, diarrhea and vomiting; and may include metabolic acidosis, convulsions, and coma after apparent recovery. Speed is essential for effective treatment which is dependent upon removing excess iron from the alimentary tract prior to absorption. Initially an emetic should be given, followed by gastric lavage with 1% sodium bicarbonate, and oral administration of desferrioxamine to complex with residue.
Pharmacology & Mechanism of Action
Iron Polymaltose Complex is a polysaccharide-iron complex, which is a novel iron preparation used in the treatment of iron deficiency anaemia. Iron, an essential constituent of the body, is necessary for haemoglobin formation and for the oxidative process of living tissue. This preparation contains non-ionic ferric iron and polymaltose in a stable complex. This facilitates a controlled absorption of the ferric iron when it comes in contact with the mucosal cell surface. Being non-ionic, it does not release any free radicals and thus takes care of all the toxic effects found due to the release of free radicals by the traditional ionized iron salt preparations. It does not interact with the food components and other medications and so, unlike ferrous salts, there is no decrease in bioavailability of Iron Polymaltose Complex. This makes sure that with the consumption of this complex, iron gets utilized at a faster rate in the haemoglobin and myoglobin synthesis.