Combicid
Cheaper & Alternative Brands
Same generic (Clobetasol Propionate + Ofloxacin + Ornidazole + Terbinafine), same form (Cream)
Clinical Prescribing Information
Medical monograph and safety information for healthcare professionals & patients.Indications & Clinical Uses
Axxo cream is indicated in the treatment of-
Mixed and complicated Fungal, Protozoal & Bacterial infections,
Mild to moderate vaginitis,
Candidiasis and trichomoniasis,
Pruritus vulvae,
Dermatitis,
Eczema,
Genito-urinary infections.
Dosage & Administration
Apply by gently rubbing onto the affected area twice daily.
Contraindications
Contraindicated in patients hypersensitive to any of the components of the formulation.
Side Effects & Adverse Reactions
Burning, itching, irritation, dry skin
Warnings & Precautions
Do not shallow. For external use only
Pharmacology & Mechanism of Action
This cream is a combination cream which exhibits anti-bacterial, anti-fungal, anti-protozoal & anti-inflammatory actions. Ofloxacin is a broad-spectrum antibiotic that acts against many gram-positive & gram-negative bacteria. Ornidazole belongs to the nitroimidazole group of antibiotics and is used to treat amoeba and trichomonas infections. Terbinafine is an Allylamine antifungal that inhibits biosynthesis of Ergosterol (an essential components if fungal cell membrane) via inhibition of Squalene Epoxidase enzyme causing fungal cell death. Clobetasol is a potent corticosteroid which exhibits anti-inflammatory, anti-pruritic and vasoconstrictive properties.