Vonoprazan + Amoxicillin
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📖 Official Clinical Monograph
DGDA Approved Prescribing GuidelinesVonomax Duo is indicated for the treatment of H. pylori infection in adults.
14 days daily administration for morning, mid-day and night dowing each containing the following two drug products:
Tablet
: Vonoprazan 20 mg
Capsule
: Amoxicillin 500 mg
The recommended dosage regimen is
Morning
: 1 Vonoprazan 20 mg tablet & 2 Amoxicillin 500 mg capsules
Midday
: 2 Amoxicillin 500 mg capsules
Night
: 1 Vonoprazan 20 mg tablet & 2 Amoxicillin 500 mg capsules with or without food, for 14 days
Known hypersensitivity to Vonoprazan, Amoxicillin or any other beta-lactams, or any component of Vonomax Duo.
Rilpivirine-containing products
Most common adverse reactions (22%) were diarrhea, abdominal pain, vulvovaginal candidiasis and nasopharyngitis.
Hypersensitivity Reactions
: Serious and occasionally fatal reactions (e.g., anaphylaxis) have been reported with components of Vonomax Duo. If hypersensitivity reactions occur, discontinue Vonomax Duo and institute immediate therapy (eg, anaphylaxis management).
Severe Cutaneous Adverse Reactions (SCAR)
: Discontinue Vonomax Duo at the first signs or symptoms of SCAR or other signs of Hypersensitivity and consider further evaluation.
Clostridioides difficile-associated diarrhea (CDAD)
: Evaluate if diarrhea occurs with Vonomax Duo.