Nebivolol + Hydrochlorothiazide
💊 Brand Formulations & Prices
7 brands sorted by unit price
Bipinor Plus
Carnovas HZ
Nebicard Plus
Nebilol Plus
Nebipres HZ
Nebita Plus
Vasocor HZ
📖 Official Clinical Monograph
DGDA Approved Prescribing GuidelinesBipinor Plus is indicated in essential hypertension.
Once daily, preferably at the same time every day. Use in children is not recommended.
Hypersensitivity to the active substances, Liver function impairment.
Severe renal insufficiency (Creatinine clearance < 30 ml/min.), Bradycardia, Hypotension
Nebivolol: Headache, Dizziness, Tiredness, Diarrhoea, Constipation, Nausea etc. Hydrochlorothiazide: Vertigo, Itchiness, Rash, Increased sensitivity of skin to sunlight etc.
Nebivolol
: Beta-blockers should not be used in patients with untreated Congestive Heart Failure (CHF) & bradycardia. In patients with Chronic Obstructive Pulmonary Diseases (COPD), beta-blockers should be used with caution as airway constriction may be aggravated.
Hydrochlorothiazide
: In patients with renal disease, thiazides may increase azotaemia. If progressive renal impairment becomes evident, careful reappraisal of therapy is necessary. Thiazides can cause fluid or electrolyte imbalance. Thiazides may decrease urinary calcium excretion and may cause slight elevation of serum calcium in the absence of known disorders of calcium metabolism
Nebivolol & Hydrochlorothiazide combination has an additive antihypertensive effect, reducing blood pressure to a greater degree than either component alone. This combination has mild vasodilating properties which reduces heart rate and blood pressure in hypertensive patients. Hydrochlorothiazide affects the renal tubular mechanisms of electrolyte reabsorption which directly increase the excretion of sodium and chloride in approximately equivalent amounts. The diuretic action of Hydrochlorothiazide reduces plasma volume, increases plasma renin activity and increases aldosterone secretion.