Homatropine Hydrobromide
Brand Formulations & Prices
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📖 Official Clinical Monograph
DGDA Approved Prescribing GuidelinesHemomin eye drops is indicated for use as a mydriatic and cycloplegic.
For refraction
: Instill two drops in the eye(s) and repeat 2-3 times at 5-10 minute intervals.
For therapy
: Instill 1-2 drops in the eye(s) every 3-4 hours.
Use in children
: Should not be used in children below the age of 3 months.
Contraindicated in patients with closed-angle glaucoma or with a narrow angle between the iris and the cornea.
Hypersensitivity may occur as conjunctivitis.
Should be used with caution in patients with prostatic enlargement and in patients suffering from paralytic ileus or pyloric stenosis.
Homatropine is a competitive muscarinic receptor antagonist with a bulky aromatic group in place of the acetyl group of acetylcholine. It is expected to act in similar manner as atropine, producing similar parasympatholytic effects. By blocking muscarinic receptors and cholinergic signalling pathways, homatropine blocks the response of the iris sphincter muscle and cause the pupil to become unresponsive to light upon dilation or mydriasis. It also blocks the accommodative muscle of the ciliary body to cholinergic stimulation.