OshudGanciclovir
Ophthalmic Anti-viral Products
Brands & Prices (7)
📋 Indications & Uses Dosage & Administration⚠️ Contraindications⚡ Side Effects & Adverse Reactions🛡️ Warnings & Precautions🔬 Pharmacology & Mechanism
Brand Formulations & Prices
7 brands sorted by unit price
Ganrux
Gansovir
Herpigel
Virovir
Xoviral
Zirgan
Genclovir
📖 Official Clinical Monograph
DGDA Approved Prescribing GuidelinesGanrux ophthalmic gel is a topical eye antiviral that is indicated for the treatment of acute herpetic keratitis (dendritic ulcers)
Dosage & AdministrationThe recommended dosing regimen for Ganciclovir eye gel 0.15% is 1 drop in the affected eye 5 times per day (approximately every 3 hours while awake) until the corneal ulcer heals and then 1 drop 3 times per day for 7 days.
It is contraindicated to the patients with known hypersensitivity to Ganciclovir.
Most common adverse reactions reported in patients were blurred vision (60%), eye irritation (20%), punctate keratitis (5%), and conjunctival hyperemia (5%).
It is indicated for topical eye use only. Patients should not wear contact lenses if they have signs or symptoms of herpetic keratitis or during the course of therapy with it.
This eye gel contains the active ingredient, Ganciclovir, which is a guanosine derivative that, upon phosphorylation, inhibits DNA replication by herpes simplex viruses (HSV). Ganciclovir is transformed by viral and cellular thymidine kinases (TK) to ganciclovir triphosphate, which acts as an antiviral agent by inhibiting the synthesis of viral DNA in two ways: competitive inhibition of viral DNA-polymerase and direct incorporation into viral primer strand DNA, resulting in DNA chain termination and prevention of DNA replication.