Cefuroxime Axetil + Clavulanic Acid

176 Registered Brands From ৳18.00 / unit

Second generation cephalosporins

Brands & Prices (176) 📋 Indications & Uses

Dosage & Administration ⚠️ Contraindications ⚡ Side Effects & Adverse Reactions 🛡️ Warnings & Precautions 🔬 Pharmacology & Mechanism

Brand Formulations & Prices

176 brands sorted by unit price

📖 Official Clinical Monograph

DGDA Approved Prescribing Guidelines

📋 Indications & Uses

Adrox CV is indicated for the treatment of infections caused by sensitive bacteria.
Pharyngitis/Tonsillitis caused by Streptococcus pyogenes.
Acute Bacterial Otitis Media caused by Streptococcus pneumoniae, Haemophilus influenzae, Moraxella catarrhalis (beta-lactamase producing strains) or Streptococcus pyogenes.
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Adrox CV is indicated for the treatment of infections caused by sensitive bacteria.
Pharyngitis/Tonsillitis caused by Streptococcus pyogenes.
Acute Bacterial Otitis Media caused by Streptococcus pneumoniae, Haemophilus influenzae, Moraxella catarrhalis (beta-lactamase producing strains) or Streptococcus pyogenes.
Acute bacterial maxillary sinusitis caused by Streptococcus pneumoniae or Haemophilus influenzae (non beta-lactamase producing strains)
Lower respiratory tract infections including pneumoniae, caused by Streptococcus pneumoniae, Haemophilus influenzae (including beta lactamase-producing strains), Klebsiella spp., Staphylococcus aureus (penicillinase- and non-penicillinase-producing strains), Streptococcus pyogenes, E. coli.
Acute bacterial exacerbation of chronic bronchitis and secondary bacterial infections of Acute bronchitis caused by Streptococcus pneumoniae, Haemophilus influenzae (beta-lactamase negative strains) or Haemophilus parainfluenzae (beta-lactamase negative strains).
Uncomplicated skin and skin-structure infections caused by Staphylococcus aureus (including beta-lactamase producing strains) or Streptococcus pyogenes.
Uncomplicated urinary tract infections caused by E.coli or Klebsiella pneumoniae.
Bone and Joint Infections caused by Staphylococcus aureus (penicillinase- and non-penicillinase-producing strains).
Uncomplicated Gonorrhoea caused by penicillinase-producing and non-penicillinase producing strains of Neisseria gonorrhoeae.
Early Lyme Disease (erythema migrans) caused by Borrelia burgdorferi.
Septicemia caused by Staphylococcus aureus, Streptococcus pneumoniae, E.coli, Haemophilus influenzae (including ampicillin-resistant strains) & Klebsiella spp.
Meningitis caused by Streptococcus pneumoniae, Haemophilus influenzae (including ampicillin-resistant strains), Neisseria meningitidis & Staphylococcus aureus (penicillinase and non-penicillinase producing strains)
Switch therapy (Injectable to oral)

Dosage & Administration

Adolescents and adults (13 years and older)-
Pharyngitis/tonsillitis
: 250 mg b.i.d. for 5-10 days
Acute bacterial maxillary sinusitis
: 250 mg b.i.d. for 10 days
Acute bacterial exacerbation of chronic bronchitis
: 250-500 mg b.i.d. for 10 days
Secondary bacterial infections of acute bronchitis
: 250-500 mg b.i.d. for 5-10 days
Uncomplicated skin and skin structure infections
: 250-500 mg b.i.d. for 10 days
Uncomplicated urinary tract infections
: 250 mg b.i.d. for 7-10 days
Uncomplicated Gonorrhoea
: 1000 mg b.i.d. Single dose
Community acquired pneumonia
: 250-500 mg b.i.d. for 5-10 days
MDR Typhoid Fever
: 500 mg b.i.d. for 10-14 days
Early Lyme disease
: 500 mg b.i.d. for 20 days
Paediatric Patients (3 months to 12 years)-
Pharyngitis/Tonsillitis
: 20 mg/kg/day b.i.d for 5-10 days
Acute otitis media
: 30 mg/kg/day b.i.d for 10 days
Acute bacterial maxillary sinusitis
: 30 mg/kg/day b.i.d for 10 days
Impetigo
: 30 mg/kg/day b.i.d for 10 days
Cefuroxime-Clavulanic Acid tablet may be taken without regard of food.

⚠️ Contraindications

Cefuroxime-Clavulanic Acid is contraindicated in patients with known allergy to cephalosporin & in patients with Pseudomembranous Colitis.

⚡ Side Effects & Adverse Reactions

Generally Cefuroxime-Clavulanic Acid is well tolerated. However, a few side effects like nausea, vomiting, diarrhea, abdominal discomfort or pain may occur. As with other broad-spectrum antibiotics, prolonged administration of Cefuroxime and Clavulanic acid combination may result in overgrowth of nonsusceptible microorganisms. Rarely (<0.2%) renal dysfunction, anaphylaxis, angioedema, pruritis, rash and serum sickness like urticaria may appear.

🛡️ Warnings & Precautions

Cefuroxime should be given with care to patients receiving concurrent treatment with potent diuretics & who has history of colitis.

🔬 Pharmacology & Mechanism

Cefuroxime is a bactericidal second generation cephalosporin antibiotic which is active against a wide range of Gram-positive and Gram-negative susceptible organisms including many beta-lactamase producing strains. Cefuroxime inhibits bacterial cell wall synthesis by interfering with the transpeptidation process.
Clavulanic acid is a naturally derived beta lactamase inhibitor produced by Streptomyces clavuligerus. It has similar structure to beta lactam antibiotics which binds irreversibly to beta-lactamase enzymes and inactivates them. Clavulanic acid gives protection of Cefuroxime from degradation by beta lactamase enzymes and provides a solution for the treatment of bacterial infections caused by beta lactam resistant bacteria.

Cefuroxime Axetil + Clavulanic Acid

Brand Formulations & Prices

Clacef

Fuclav

Cefaclav

Clavusef

Furotil Plus

Cerox CV

Furoget CV

Relacef Plus

Ceclav

Cefuson Plus

Claviator-CV

Clavimax-CV

Cosmotil

Eurix CV

Meroclav

Neoclav

Probac Plus

Rapiclav

Roximax Plus

Staxiclav

Clavuxet

Recofast CV

Sharpkil Plus

Cefurim CV

Clavuxim

Clavucure

Doctil Plus

Fuxtil CV

Cefurav Plus

Fixcef Plus

Ximeclav

Axeclav

Axim CV

Brocef CV

Cefaclav

Cefotil Plus

Cefusil CV

Cefuxet Plus

Ceroclav

Cerox CV

Clacef

Clavurox

Clavusef

Clavutil

Co-Axet

Famiclav

Fuclav

Furoclav

Furotil Plus

Kefuclav

Mexclav

Nucef CV

Roclav

Roxibac Plus

Roxiclav

Turboclav

Xiclav

Xinarox CV

Zinaclav

Cefuxim-CV

Axicef Plus

Benkill CV

Roxilab Plus

Secoclav

Zerotil Plus