Brivaracetam

16 Registered Brands From ৳30.00 / unit ⚕️ Adjunct anti-epileptic drugs
💊 Brands & Prices (16) 📋 Indications & Uses⚠️ Contraindications⚡ Side Effects & Adverse Reactions🛡️ Warnings & Precautions🔬 Pharmacology & Mechanism

💊 Brand Formulations & Prices

16 brands sorted by unit price

📖 Official Clinical Monograph

DGDA Approved Prescribing Guidelines
📋 Indications & Uses

Bivara is indicated for the treatment of partial onset seizures in patients 1 month of age and older.

⚠️ Contraindications

Brivaracetam is contraindicated in patients with known hypersensitivity to brivaracetam or any other components of this product.

⚡ Side Effects & Adverse Reactions

The most common side effects are nausea/vomiting, constipation, somnolence and sedation, dizziness, fatigue, cerebellar coordination and balance disturbances and irritability.

🛡️ Warnings & Precautions

Antiepileptic drugs (AEDs), including Bivara, increase the risk of suicidal thoughts or behavior. Patients treated with any AED should be monitored for the emergence or worsening of depression, suicidal thoughts or behavior and/or any unusual changes in mood or behavior. Bivara causes somnolence, fatigue, dizziness and disturbance in coordination. Patients should be monitored for these signs and symptoms and advised not to drive or operate machinery. Bivara causes psychiatric adverse reactions which included both non-psychotic symptoms (irritability, anxiety, nervousness, aggression, belligerence, anger, agitation, restlessness, depression, depressed mood, tearfulness, apathy, mood swings, psychomotor hyperactivity, abnormal behavior and adjustment disorder) and psychotic symptoms (psychotic disorder along with hallucination, paranoia, acute psychosis and psychotic behavior). As with most antiepileptic drugs, Bivara should generally be withdrawn gradually because of the risk of increased seizure frequency and status epilepticus.

🔬 Pharmacology & Mechanism

This is a preparation of Brivaracetam which is an anticonvulsant. The precise mechanism by which Brivaracetam exerts its anticonvulsant activity is not known. Brivaracetam displays a high and selective affinity for synaptic vesicle protein 2A (SV2A) in the brain which may contribute to the anticonvulsant effect.