Abametapir
💊 Brand Formulations & Prices
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📖 Official Clinical Monograph
DGDA Approved Prescribing GuidelinesLyby is a pediculicide indicated for the topical treatment of head lice infestation in patients 6 months of age and older. Lyby should be used in the context of an overall lice management program:
Wash (with hot water) or dry-clean all recently worn clothing, hats, used bedding and towels
Wash personal care items such as combs, brushes and hair clips in hot water
Use a fine-tooth comb or special nit comb to remove dead lice and nits.
For topical use only. Not for oral, ophthalmic, or intravaginal use.
Shake well before use.
Apply LYBY to dry hair in an amount sufficient (up to the full content of one bottle) to thoroughly coat the hair and scalp. Avoid contact with eyes.
Massage LYBY into the scalp and throughout the hair; leave on the hair and scalp for 10 minutes and then rinse off with warm water.
Treatment with LYBY involves a single application. Discard any unused product. Do not flush contents down sink or toilet.
The most common side effects of Lyby include: Redness of the skin or scalp, rash, burning sensation of the skin, skin irritation, vomiting, eye irritation, itchy scalp, changes in your hair color.
Risk of Neonatal Benzyl Alcohol Toxicity
: Systemic exposure to benzyl alcohol has been associated with serious adverse reactions and death in neonates and low birth-weight infants. Safety and effectiveness in pediatric patients below the age of 6 months have not been established.
Use is not recommended in pediatric patients under 6 months of age because of the potential for increased systemic absorption.
Risk of Benzyl Alcohol Toxicity from Accidental Ingestion
: Administer only under direct supervision of an adult.
Abametapir (5, 5’-dimethyl 2, 2-bipyridinyl) is a metalloproteinase inhibitor Metalloproteinases have a role in physiological processes critical to egg development and survival of lice.